General Cell Based Assays
Eurofins Discoverx PathHunter Human GPR17 β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human GPR17 β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure GPR17 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Amsbio LLC Cupric Iron Chelating (CIC) Assay Kit -store kit components as indicated
Cupric Iron Chelating (CIC) Assay Kit -store kit components as indicated
Eurofins Discoverx PathHunter CXCR5 Bioassay Kit, 10-Plate. (93-0514Y2-00064)
The PathHunter CXCR5 Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. CXCL13) based activation of CXCR5 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CXCR5 and EA-tagged β-Arrestin-2. Activation of CXCR5 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx cAMP Hunter™ Human PTGER3 Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human PTGER3 Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure PTGER3 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human GPR20 β-Arrestin Cell-Based Assay Kit (HEK 293)
The PathHunter Human GPR20 β-Arrestin Stable Cell Line Assay (HEK 293) contains a stable clonal cell line used to measure GPR20 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
MOLTOX Molecular Toxicology Inc 60-251.4L - Lyophilized NADPH REGENSYS B Plus. Intended for use in EAT testing. Supports 5-30% S9 mix. 40ml refers to final volume of S9 mix/pkg. 140mg of crystalline NADP. Add to A Plus. Store in freezer.
60-251.4L - Lyophilized NADPH REGENSYS B Plus. Intended for use in EAT testing. Supports 5-30% S9 mix. 40ml refers to final volume of S9 mix/pkg. 140mg of crystalline NADP. Add to A Plus. Store in freezer.
Eurofins Discoverx PathHunter Human GPR150 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR150 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR150 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human OPRK1 (Opioid Kappa) β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human OPRK1 (Opioid Kappa) β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure OPRK1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress GPR61 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0407E2ACP1L)
The PathHunter GPR61 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR61 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR61 and EA-tagged β-Arrestin-2. Activation of GPR61 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc LANCE Ultra Phospho-SMAD2 (Ser465/467) Detection Kit, 10,000 Assay Points
LANCE Ultra Phospho-SMAD2 (Ser465/467) Detection Kit, 10,000 Assay Points
Eurofins Discoverx PathHunter eXpress PTGER3 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0640E2CP0L)
The PathHunter PTGER3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. prostaglandin E2) based activation of PTGER3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PTGER3 and EA-tagged β-Arrestin-2. Activation of PTGER3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam SIRT2 Activity Assay Kit (Fluorometric)
SIRT2 Activity Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter Mouse S1P1 (EDG1) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Mouse S1P1 (EDG1) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure EDG1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Cayman Chemical 8-propylthio NAD sodium sal
A derivative of NAD+; has been used in the screening of analog-sensitive PARP1 gatekeeper mutations
Eurofins Discoverx PathHunter eXpress CHRM4 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0349E2CP0L)
The PathHunter CHRM4 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. acetylcholine) based activation of CHRM4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CHRM4 and EA-tagged β-Arrestin-2. Activation of CHRM4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.